宮永一彦先生

自治医科大学 医学部 感染・免疫学講座 細菌学部門 准教授

主な研究内容：

• 環境微生物
• 金属の微生物腐食
• バクテリオファージの工学的応用

論文

1. Tanji Y, Murofushi K, Miyanaga K. Quick selection of a chimeric T2 phage that displays active enzyme on the viral capsid. Biotechnol Prog. 2005; 21:1768-1771.
2. Miyanaga K, Hijikata T, Furukawa C, Unno H, Tanji Y. Detection of Escherichia coli in the sewage influent by fluorescent labeled T4 phage. Biochem Eng J. 2006; 29:119-124.
3. Miyanaga K, Takano S, Morono Y, Hori K, Unno H, Tanji Y. Optimization of distinction between viable and dead cells by fluorescent staining method and its application to bacterial consortia. Biochem Eng J. 2007; 37(1):56-61.
4.  Miyanaga K,Terashi R,Kawai K,Unno H,Tanji Y. Effects of pH increase derived from cathodic protection on bacterial viability in proximity to carbon steel. Biotechnol Bioeng. 2007; 97(4): 850-857.
5. Hu J, Miyanaga K, Tanji Y. Diffusion of bacteriophages through artificial biofilm models. Biotechnol Prog. 2012; 28(2):319-326.
6. Tanji Y, Tanaka A, Tani K, Kurimoto M, Miyanaga K. IgG-dependent aggregation of Staphylococcus aureus inhibits bacteriophage attack. Biochem Eng J. 2015; 97:17-24.
7. Azam AH, Hoshiga F, Takeuchi I, Miyanaga K, Tanji Y. Analysis of phage resistance in Staphylococcus aureus SA003 reveals different binding mechanism for the closely related Twort-like phages ΦSA012 and ΦSA039. Appl Microbiol Biotechnol. 2018; 102(20):8963-8977.
8. Ung P, Peng C, Yuk S, Tan R, Ann V, Miyanaga K, Tanji Y. Dynamics of bacterial community in Tonle Sap Lake, a large tropical flood-pulse system in southeast Asia. Sci Total Environ.2019; 664,:414-423.
9. Peng C,Hanawa T,Azam AH,LeBlanc C,Ung P,Matsuda T,Onishi H, Miyanaga K, Tanji Y. Silviavirus phage ΦMR003 displays a broad host range against methicillin-resistant Staphylococcus aureus of human origin. Appl Microbiol Biotechnol. 2019; 103(18):7751-7765.
10. Nishio J, Negishi H, Yasui-Kato M, Miki S, Miyanaga K, Aoki K, Mizusawa T, Ueno M, Ainai A, Muratani M, Hangai S, Yanai H, Hasegawa H, Ishii Y, Tanji Y, Taniguchi Y. Identification and characterization of a novel Enterococcus bacteriophage with potential to ameliorate murine colitis. Sci Rep. 2021; 11(1):1-13.